At Therion we are driven by our mission to Extend and Improve the Lives of Cancer Patients. If you are interested in a fast-changing, dynamic environment in a biotechnology company that is pioneering novel immune therapies for cancer, then Therion is the right company for you.

We are seeking a strong Process Development professional to be responsible for upgrading the manufacturing process to improve efficiency and GMP compliance for Phase III clinical trials and commercial scale manufacturing of recombinant poxvirus vaccines for cancer and AIDS. Develop and implement purification aspects of process development including filtration, chromatography and centrifugation. Responsible for the definition, development and optimization of processes and equipment from the laboratory through pilot plant and manufacturing scale. Analyzes and compiles process data, identifying major variables in processes and present alternatives. Produces process flow diagrams with material balances for manufacturing processes. Identifies and resolves issues with materials, processes, and equipment. Performs experiments, prepares test samples, maintains inventory of materials on a regular basis and operates equipment as required. Executes process validation/equipment qualification processes and maintains files of lab tests, work procedures, formulations, calculations and assembly methods.
Responsible for routine maintenance of all equipment used. Maintains appropriate records and documentation to comply with regulatory requirements, GMPs, and standard operating procedures and assists in writing procedures as necessary. Interact with manufacturing operations in the technical transfer of the product to manufacturing.

We are looking for candidates that embrace our core values of Integrity, Innovation, Collaboration, Compassion, Commitment and Excellence we also ask that you have a BS/MS in Biology or related discipline with 8+ years of experience, Ph.D. preferred with 4+ years of experience in process/product development in a biotechnology/pharmaceutical environment regulated by FDA/CBER. Strong knowledge of mammalian cell culture and virus purification. Experience with stir tank technology is a plus. Knowledgeable in translating bench/small scale manufacturing into large scale, GMP production.
Knowledge of and experience with Good Manufacturing Practices, industrial safety regulations and practices. Excellent leadership, interpersonal and communication skills; strong training and presentation skills; and proven MS Project, Excel, PowerPoint, and Word software skills. Ability to work cooperatively in a matrix environment.
Established ability to prioritize and manage multiple tasks simultaneously, and demonstrated ability to identify and resolve project issues. Strong initiative and a can-do attitude, excellent organizational skills, proven effectiveness in a quick-changing, fast-paced environment, and a proven record as a team player are also essential.

For full immediate consideration, interested, qualified candidates are encouraged to email their resume and cover letter to:

[email protected]
Therion Biologics Corporation
Human Resources
76 Rogers Street
Cambridge, MA 02142
Fax: (617) 475-7249

For more information on Therion please see our website at www.therionbio.com

Therion is an equal opportunity employer.